Erected 1871, before Del Rio was founded, by John Perry, as General Store. Once the largest store between San Antonio and El Paso. Served also as courthouse, church, Masonic lodge, and post office. Given in 1965 to city and county by descendants of Walter and Will Whitehead. Recorded Texas Historic Landmark, 1966.

The Old Perry Building/Store is a Recorded Texas Historical Landmark.

The Old Perry Building/Store is one of the oldest buildings in Del Rio and is a part of the Whitehead Memorial Museum on South Main Street (which used to be called Perry Street).